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Pau D´Arco - Lapacho
Pau D´Arco - Lapacho in brief
Scientific name: Tabebuia avellanedae Lor. Ex Grieseb
Family: Bignoniaceae
Popular names: Pau D’Arco, Ipe Roxo, Tahuari, Taheebo, Lapacho
Used parts: Bark.
Botanical characteristics: It's a wild tree with gray wood and opposite leaves. It has flowers of rosy, purple or lilac coloration. The fruit is lineal and cylindrical.
Habitat: It is common in many Brazilian area and northwest and northeast of Argentine.
Chemical composition: It contains iridoids, cyanidin, 3- rutinoside, anthocyanins, alkaloids, lapachol, anthraquinones, naphtoquinones, beta-sitosterol, chromium, chrysophanic, saponins, flavonoids, cumarines, quercetin, iridoids.
Therapeutic indications: immunostimulant, antimutagenic, antileukemic antitumoral, anticarcinogenic analgesic, antibacterial, antifungal, antiviral, antiparasitic, anti-inflammatory, antirheumatic, antiviral, laxative, antioxidant. It acts as antioxidant and in cases of prostate cancer.
Dose: Tea for decoction. Boil 50 g with one liter of water and drink several times a day, preferentially 6 to 8 daily glasses. Fluid extract 2 – 10 ml/day, Tincture 10 – 30 ml/ day
Other information: According to accomplished researches, it was discovered a well-known substance named Lapachol that possesses pharmacological properties, among the ones the power to inhibit the growth of malign tumors, at the same time that reduces the pain. This substance avoids that the hormones related to cancer links to the normal cells.
References:
LORENZI, H.; MATOS, A. F. J. Plantas Medicinais no Brasil. 2002, p. 325.
MACHADO, T. B. et al. In vitro activity of Brazilian medicinal plants, naturally occurring naphthoquinones and their analogues, against methicillin-resistant Staphylococcus aureus. Antimicrobial Agents. 2003, 21, p. 279-284.
MIRANDA, F. G.F. et al. Antinociceptive and antiedenatogenic properties and aute toxicity of Tabebuia avellanedae Lor. Ex Grieseb. Inner bark aqueous extract. BMC Pharmacology. 2001,1:6.
MOREIRA, E. A.; DEFREITAS, B.; CAMATI, M. R. Análise Fitoquímica Sumária do Córtex do Ipê Roxo. Tribuna Farmacêutica. 1967, v. 1-2, p.23-26.
NAKANO, K. et al. Iridoids from Tabebuia avellanedae. Phytochemisty, 1993, vol 32, p. 371-373.
OLIVEIRA, DE F.; AKISUE, G.; AKISUE, K. M. Farmacognosia. Editora Atheneu. 1991, p. 293 – 297.
POMILIO, A.B.; SPROVIERO, J.F. Anthocyanins from Argentine Tabebuia species. Phytochemistry. vol.10, p. 1399-1400.
STEINERT, J.; KHALAF, H.; RIMPLER, M. High performance liquid chromatographic separation of some naturally occurring naphthoquinones. Journal of Chromatography A. 1996, 723, p. 206-209.
UEDA, S. et al. Production of Anti-tumor-promoting Furano-naphthoquinones in Tabebuia avellanedae cell cultures. Phytochemistry, 1994, vol. 36, 2, p. 323-325.
06.6.2008

